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doi: 10.1002/jhm.228

It is important to note that an impact of the Inflation Reduction Act is that small molecule therapeutics may continue to be deprioritized in favor of biologics, so development of oral biologics may (unfortunately) be more compelling for companies in this context

The Effects of Growth Hormone on Adipose Tissue: Old Observations, New Mechanisms

5f, g, Supplementary Table 4)

Acknowledgment Not applicable

Many cyanobacteria (and microalgae broadly) are safe to eat, though not every strain of cyanobacteria has a GRAS certification.5 Under the GRAS framework, an ingredient has to be demonstrated as safe either through (1) scientific procedures or (2) in the case of a substance used in food prior to January 1, 1958, through experience based on common use in food. For cyanobacteria to be used as a platform for oral GLP-1 delivery, either a GRAS organism like spirulina must serve as the host organism or, if choosing a different species, the manufacturer must prove with adequate in vivo trial data that it is safe to eat
