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This Phase 1 trial, completed on an accelerated timeline, marks a key milestone in validating both the safety and translational potential of Hanmis next generation triple agonist in humans

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Addressing obesity through weight management strategies, including pharmacologic ones like GLP-1 receptor agonists, is a key component of reducing all operative risks, improving surgical outcomes, and enhancing the long-term success of orthopedic interventions

I think the bump in the road was really the development of oral semaglutide, which showed that you could give oral GLP-1 and have pretty impressive pharmaceutical activity, he said