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If you experience severe, unrelenting abdominal pain, seek immediate medical attention

GIP co-activation may also attenuate the gastrointestinal adverse reactions including nausea, vomiting, or diarrhea most commonly reported during dose escalation with GLP-1 receptor agonists

Blood sugar stabilization Chronically elevated blood sugar, even at levels that do not meet the diagnostic threshold for diabetes, causes persistent low-grade fatigue

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Thus far, the effect of tirzepatide on cardiovascular risk factors has indicated improvements in lipids, lipoprotein profiles, glucose control, body weight, blood pressure, and several biomarkers of inflammation in adults with overweight or obesity both with and without T2D (Tables 1, 2, 3, 4)

Tirzepatide was associated with a 16% lower rate of all-cause mortality compared to dulaglutide