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He is, in other words, no reflexive skeptic of these drugs, which is exactly what makes his account of their limits worth hearing

Other red flags: uncontrollable vomiting , inability to keep fluids down, worsening weakness or dehydration

All statistics and clinical interpretations are sourced from published Phase 2 and Phase 3 trial results as of October 2025

B.VillateO.LlanoI.OcioI.MartI.et al

Thyroid C-cell tumor risk (rodent-only findings) carries class-wide warning

Nutrient deficiencies associated with obesity may be partly due to consumption of a poor-quality diet that is high in calories but has a low nutrient density