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Track skin changes monthly to fine-tune diet, fluids, and exercise, or supplement with non-surgical treatments like light therapy, chemical peels, or radiofrequency when laxity remains

For patients interested in exploring dual-compound therapy, PlexusDx offers GLP-Squared Injection (semaglutide plus tirzepatide compounded together), which starts at $249/month

Healthcare providers prescribing tirzepatide should document baseline eye examination status, ensure patients have established ophthalmologic care, and reinforce the importance of maintaining regular eye examinations as part of comprehensive diabetes and metabolic disease management

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This pattern holds across most GLP-1 medications, indicating that sustained medication use is the primary driver of sustained weight loss

Riley RD, Higgins JPT, Deeks JJ (2011) Interpretation of random effects meta-analyses