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Biologic sta

Mechanistic studies found that BA1b promoted the secretion of incretin (GIP and GLP-1) by up-regulation of VDAC1 gene expression levels
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Compared with placebo, semaglutide showed significant reductions in body weight (ETD2.85 kg

Genetic instruments were derived from cis-eQTLs for GLP-1R, and analyses were conducted using large-scale GWAS datasets
