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Referring to taking semaglutide, "Real Housewives of Beverly Hills" star Crystal Kung Minkoff told Page Six: "Of course I've thought about it." But she said as someone who has struggled with an eating disorder her whole life "it's not a good place for me, personally for my recovery." She told Page Six that she'd always looked for things to "fix it" for her, but added that she's currently in a "really good place" with her eating disorder recovery

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[DOI] [PMC free article] [PubMed] 66.Glucagon-Like Peptide 1 Receptor (GLP-1R) Agonists in Type 2 Diabetes and Obesity in Major Markets, Disease Overview and Drug Forecast to 2033

HRT typically improves energy levels, so the combination should theoretically be net positive for energy

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And while forgetting to refrigerate a pen for a few hours may not always be a problem, heat is a different story