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Description
At a 10 mg/mL concentration, one extra unit only adds 0.1 mg

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This investigational drug is distinctive in targeting GIP, GLP-1, and glucagon receptors, a novel approach compared to existing obesity treatments

Retatrutide activates three receptors, offering broader metabolic support and potentially greater fat loss

Trial Data: REDEFINE 1 vs Nothing REDEFINE 1 (Cagri+Sema, Phase 3) Garvey et al., NEJM 2025

Importantly, tirzepatide can reduce the exposure to oral contraceptives after initiation and dose escalation
