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this model can also be used to provide patients with precise and individualized treatment and to build rapid in vitro test models for drug screening or gene/cell therapy, linking basic research with clinical treatment

These delays highlight the structural barriers that can slow adoption in populations with higher rates of comorbidities

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Findings reported in preclinical and experimental models emphasize how multi-receptor activation can influence metabolic signaling networks, feedback loops, and pathway cross-talk under laboratory conditions