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illustrated treating depressed patients with SSRI escitalopram shifted gut microbiota to produce more indole-3-propionic acid (I3PA) [200], while excess I3PA could lead to obesity and hepatic fibrosis [202, 203]

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Ankylosing spondylitis is an inflammatory condition that causes pain and stiffness in the spines joints

Some studies have suggested that the proliferation and apoptosis of granulosa cells (GCs) are the root causes of follicular development and atresia, with forkhead box protein O1 (FoxO1) playing an important role in promoting PCOS follicular atresia and GCs apoptosis (162, 163)

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In autoimmune disease, the balance tilts heavily toward M1