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Evolution of GLP-1-based therapeutics First-generation GLP-1RAs The development of GLP-1 receptor agonists stemmed from the significant finding that natural GLP-1 had an exceptionally short half-life of about 1.5 to 5 min, due to its rapid degradation by the enzyme DPP-4 (Campbell and Drucker 2013) (Fig

One key lesson is that historic demand baselines are less reliable when behavioural shifts occur at scale

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PS, propensity score

Browning refers to caramelization and related chemical reactions that create color and flavor

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