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The Zepbound (weight management) formulation reports slightly higher rates of around 4 to 5%, likely because patients are maintained at higher doses for longer periods

At the core, these cases focus on failure-to-warn

Cost and the question of how public programs should prioritize competing needs are genuine concerns

However, in the studies that reported the use of a specific medication, the most frequently used SGLT2i was dapagliflozin (10/54), followed by empagliflozin (5/54) and canagliflozin (5/54) and the most frequently used GLP1-RA was exenatide (10/54) followed by semaglutide (6/54) and liraglutide (5/54)

This decision underscores the medications established safety profile across various levels of kidney function

Santoro A, McGraw TE, Kahn BB