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Acknowledgment The authors gratefully acknowledge the Scientific Publishing Department, Health Research Center, Ministry of Defense Health Services, Riyadh, Saudi Arabia, for the English language editing

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These effects are present while the medication is active in your system, but the underlying biological drivers of obesityincluding genetic factors, metabolic adaptations, and appetite regulationtypically persist after discontinuation

The candidate, ribupatide, also called KAI-9531, works by targeting the GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors, thereby mimicking the hormones that regulate appetite in the brain and intestines just like Zepbound

And if you are following the broader wave of metabolic and longevity technology, see What Whoop's $575M Raise Means for Your Concierge Doctor

How GLP-1 Drugs Like Ozempic Are Changing Relationships, Sex, and Dating Wednesday, August 20, 2025