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[DOI] [PMC free article] [PubMed] [Google Scholar] Cani & Knauf (2021).Cani PD, Knauf C

Consult your GP or registered dietitian to determine appropriate targets for your individual circumstances

GLP-1 medications typically require 12 weeks at the target therapeutic dose to assess effectiveness

If genuine tachyphylaxis is confirmed, strategies include dose escalation to the next tier, brief treatment breaks of 2 to 4 weeks to allow receptor resensitization, or switching to alternative GLP-1 agonists like semaglutide to provide different receptor activation patterns

Side effects and safety profile AOD 9604 is generally well-tolerated

If you are going to drink, stick to one or two drinks to minimize negative effects on blood sugar, digestion, and weight loss progress