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Exercise also increases glucose tolerance and insulin sensitivity (the ability of cells to respond to insulin) and decreases insulin resistance

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It mimics the GLP-1 hormone that our bodies naturally produce in the gut

Semaglutide works through appetite and glucose regulation pathways that don't require a functioning thyroid

Because there is a lack of research on how these therapies might affect a developing fetus or a nursing infant, the safest approach is to avoid them entirely during this time

In total, 37 participants received semaglutide and 38 participants received placebo (ESM Fig
