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Description
They have mechanistic plausibility via their effects on central sensitization and neuroinflammation
Studies show that people with obesity lose heat less quickly, and need to raise their metabolism significantly less to keep warm than leaner individuals

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doi: 10.1111/j.1365-2265.2011.04313.x 53 GrugniGBeccariaLCorriasACrinACappaMDe MediciCet al
