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Follow your physicians guidance
Trial reports show that gastrointestinal adverse events were most common during dose escalation and decreased over time
Individuals consuming under 1,000 kcals/d likely function in a catabolic state and the protein-sparing effect of carbohydrates is lost
Most patients tolerate semaglutide well once at maintenance dose, with satisfaction and energy improvements offsetting early adjustment symptoms
If nausea persists beyond three weeks or you experience constipation, your provider may adjust your dose timing or recommend dietary modifications rather than pausing the medication
