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Although there is no evidence supporting a correlation between genotype and body fat distribution or obesity, research has suggested that certain genetic mechanisms involving the MKRN3 and MAGEL2 genes, as well as Small Nucleolar RNAs, may play a role in controlling body weight ( Obesity is the initial stage leading to MetS and T2DM

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Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats