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PubMed Thomas, M.K., Nikooienejad, A., Bray, R., Cui, X., Wilson, J., Duffin, K., et al

d For the GLP-1 RA component only

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Lutter M., Nestler E.J

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In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin

For Naltrexone/Bupropion comparisons, Tirzepatide showed associations with reduced cataract incidence, particularly in individuals without prior GLP-1 RA exposure (HR 0.18, 95% CI 0.050.60) and those without proteinuria (HR 0.34, 95% CI 0.130.85)