how does semaglutide work for weight loss reddit not feeling like I'm losing fast enough : r/Semaglutide does liquid semaglutide work Tirzepatide

This is a useful comparison to make directly

Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates

The primary endpoint was the mean change in HbA1c from baseline to week 52 for tirzepatide relative to insulin lispro ( 4.7 SURPASS J-mono trial in Japan In Japan, the SURPASS J-mono trial enrolled 636 Japanese adults with type 2 diabetes (age 20 years) who discontinued oral monotherapy or were treatment-naive due to hyperglycemia ( 4.8 SURPASS J-combo trial in Japan The SURPASS J-combo trial included 443 Japanese adults with type 2 diabetes (age 20 years, BMI 23 kg/m 2 , inadequately controlled HbA1c), who received tirzepatide 5 mg, 10 mg, 15 mg in addition to oral antidiabetic drugs for 3 months

Patrick Carroll, Chief Medical Officer of Hims & Hers

These results demonstrated that not only the resting levels but also the GLP-1-induced activation levels of ARNA were greater in HF compared to Sham

This triple-receptor agonism differentiates retatrutide from other weight loss medications that typically target a single pathway