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redox biology in pathologic hepatocytes and implications for intervention

the median BMI was 37.0 kg m 2 (33.7, 41.4) at baseline, 180 (34.0%) had class I obesity, 171 (32.3%) had class II obesity and 178 (33.7%) had class III obesity

Da diese Medikamentengruppe eine besondere Rolle in der Therapie der Adipositas einnimmt, besteht derzeit die Frage, welche Patient/-innen prioritr Zugang zu diesen Medikamenten erhalten sollten

Zanchi A, Burnier M, Muller ME et al (2020) Acute and chronic effects of SGLT2 inhibitor empagliflozin on renal oxygenation and blood pressure control in nondiabetic normotensive subjects: a randomized, placebo-controlled trial
However, the effect on kidney outcomes which were assessed as a five-point composite including 50% eGFR decline, kidney failure, or death from kidney causes, was not statistically significant (HR: 0.91

Gastric bypass surgery enhances glucagonlike peptide 1stimulated postprandial insulin secretion in humans
