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2019;11(12) doi: 10.3390/nu11122971

Although a single RCT failed to observe a statistically significant improvement in HOMA-IR (85), this discrepancy is more likely attributable to limited sample sizes, restricted follow-up windows, and heterogeneity in baseline metabolic phenotypes rather than a lack of efficacy

While our program does recommend healthy eating habits, its not about extreme dieting

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Ibuprofen (200400 mg every 68 hours with food, maximum 1.2 g daily for over-the-counter use) may be used if paracetamol proves insufficient, provided you have no contraindications such as kidney disease, cardiovascular conditions, gastric ulcer history, or pregnancy (especially after 20 weeks)