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Side Effects Both medications share similar side effect profiles: Nausea (usually mild and temporary) Diarrhea or constipation Decreased appetite Fatigue during initial weeks Tirzepatide may cause slightly more gastrointestinal effects initially due to its dual-action mechanism, but most patients adapt within 2-4 weeks

Formal appeals take 30 to 60 days to process

There were a few minor side effects early on, but they faded quickly

If this story sounds familiar, its because the OFA also filed a lawsuit against the FDA when tirzepatide was removed from the federal drug shortage list in 2024

[DOI] [PubMed] [Google Scholar] 29.Smits M.M., Tonneijck L., Muskiet M.H., Kramer M.H., Pouwels P.J., Pieters-van den Bos I.C., Hoekstra T., Diamant M., van Raalte D.H., Cahen D.L