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Given the emerging concern around potential muscle loss, strategies to mitigate reductions in FFM during pharmacologically induced BW loss should be prioritized

The difference in HbA1c change was 0.27% between the two groups (95% CI 0.23, 0.77), but without statistical significance (p = 0.886)

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In 2014, the Stimulation Therapy for Apnea Reduction (STAR) trial found that, among patients with moderate-to-severe OSA and a body mass index (BMI) of less than 32 kg/m 2 , unilateral hypoglossal nerve stimulation led to a 68% reduction in OSA severity (based on AHI) at 12 months, and improvements in sleepiness scores [44]
doi: 10.1016/j.eclinm.2023.101882 [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Aronne LJ, Sattar N, Horn DB, et al