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PPG NTS neurons suppress eating without behavioural disruption The observation that PPG NTS neurons selectively encode satiation during large meals, but apparently do not control intake under ad libitum eating conditions, suggests they have capacity to suppress eating when stimulated

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Short-acting and prolonged-acting GLP-1 receptor agonists (GLP-1RAs) have been developed

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Reported complications include acute pancreatitis, severe gastroparesis (delayed stomach emptying), acute kidney injury from dehydration, and thyroid complications