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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

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These comorbidities are interlinked ...

Arboviruses often co-circulate, but cross-reactivity hampers serological diagnostics

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This case raises concern about potential severe GI motility complications associated with Zepbound, particularly in the absence of conventional SBO risk factors.