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These agents bind to GLP-1 receptors expressed throughout the body, including pancreatic beta cells, the gastrointestinal tract, and central nervous system regions involved in appetite regulation

Across diabetes and obesity, there are ~20 novel GLP-1 agonists and multi-agonists in Phase 2/3 development (see image 2) , with a host more in earlier stages

There are plenty of other good alternatives too, says New York Citybased Samantha Heller, RD

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& Sharma, A

Now the pharmaceutical GLP one receptor agonists, they mimic this natural occurring GLP one and they amplify its effects