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Nausea is the most reported side effect, occurring in 12-18% of patients in clinical trials, with higher rates at larger doses

In particular, Caveolin 1 (Cav-1) binds several signaling and structural proteins through the caveolin-binding motifs, a conserved sequence enriched with aromatic residues [XXXXX, XXXXXX, and XXXXXXX ( = aromatic residue, X = any amino acid)], found in a lot of proteins, including the GLP-1 receptor

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In the cross-sectional study, Lin and colleagues examined deidentified claims data from 17 million deidentified adults between 2022 and 2023