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Clean safety: No signals of ALT, AST, or bilirubin elevation

Available at: Assessed on 5 May 2020

The baseline data show that the study population has a high cardiovascular risk, with an average age of 62 years, BMI of 33 kg/m, 76% having a prior myocardial infarction, 23% a prior stroke, and 24% chronic heart failure

When multiple risk factors overlap in a single patient (for example, a 55-year-old post-menopausal woman who is sedentary and losing weight rapidly on semaglutide without a structured exercise program), the conversation about bone and muscle protection becomes essential, not optional

The model used fixed effects of the outcome variable and the interaction of treatment and time with random effects of each participant, and for ADC and ASL analysis also layer number
