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For most licensed weight loss medicines, menstrual changes are not a direct pharmacological effect of the drug itself, but rather a secondary consequence of significant or rapid weight loss and the associated changes in energy availability and body composition

[1] [2] These agents work by mimicking the action of the naturally occurring incretin hormone GLP-1, which is released from the intestine in response to food intake

Eligible patients will fall into three cohorts

Only 84% as many patients are active on insulins at month 12 as compared to month 0 of GLP1 therapy

You would face a choice between hair and weight loss benefits

Barriers such as health care availability, economic limitations, and surgical invasiveness prohibit bariatric surgery from being widely implemented to solve the worldwide obesity epidemic