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We demonstrate that the therapeutic potential of GLP-1RAs in RA is mediated by their dual targeting of two key pathological pathways: suppressing a previously unidentified cGAS-STING-ferroptosis axis in chondrocytes and reprogramming synovial macrophages toward an M2 reparative phenotype, which collectively helps maintain joint homeostasis

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A salad topped with beans, avocado, and pumpkin seeds, or a smoothie blended with fruit, greens, and plant-based protein, are great examples of meals that may support natural GLP-1 release

Passclaim--body weight regulation, insulin sensitivity and diabetes risk

What to expect at each dose level Most people notice the first effects of tirzepatide within 1-2 weeks of their initial dose

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