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However, an oral intake of 250 mg NMN once daily in elderly men over 65 years old for 12 weeks increased whole blood NAD + and NAD + -related metabolite levels, improving gait speed and performance in the left grip test without any deleterious effects [189]

Liu B, Yang T, Luo Y, Zeng L, Shi L, Wei C, et al

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60 Similarly, defection of insulin-stimulated GLUT4 translocation to the cell surface occurs in skeletal muscle in various IR mice models 61,62 and humans with T2DM