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Donovan includes a thought-provoking assessment of the effects of the GLP-1s in equality and society, calling out that, In most societies there is prejudice against people who are overweight or obese, more pronounced the case for women The more anti-obesity drugs are used recreationally rather than as a prescription written for obesity, the more likely patients will have to pay for the drugs out-of-pocket restricting recreational access to people with higher incomes Social media has raised the importance of physical appearance and for some people increased the perceived importance of appearances

Adiposity & Body Composition Animal and clinical trial datasets describe substantial reductions in fat mass over 24- and 48-week protocols, with investigators attributing the magnitude to combined incretin and glucagon-receptor effects on intake and expenditure

A retrospective cohort study found GLP-1R agonists were associated with lower risks of cardiovascular or psychiatric comorbidities, lower mortality among patients with psoriasis.

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