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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Kim Y.K., Kim O.Y., Song J

As Dr Al-Aly put it, Biology is too complex. More and more research is starting to emerge suggesting that GLP-1RAs could have a host of other medical uses

Now, theyre widely used for weight loss and to manage conditions like heart and liver disease

As of January 2026, retatrutide for research remains investigational, undergoing Phase 3 trials

de Maio M, DeBoulle K, Braz A, et al

Glucagon secretion increases quickly following food intake and is directed primarily to the liver in order to stimulate hepatic glycogenolysis during meals [78]
