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Typically affects one eye but can occur in both

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These studies are all Cardiovascular Outcomes Trials, which are large multi-country and multi-center RCTs

GDF15 mediates the effects of metformin on body weight and energy balance

Importantly, the continued placement of pancreatogenic diabetes within the ADA category of other specific types has contributed to systematic under-recognition and misclassification, most commonly as advanced Type 2 diabetes
