why are glp 1 drugs so expensive GLP1 Expensive? The Complex World of PBMs with Josh Sanders, PharmD Growth, Volume, Price: The Skinny

Dietary intake by patients taking GLP-1 and dual GIP/GLP-1 receptor agonists: A narrative review and discussion of research needs

Studies in mice and humans showed that GLP-1 liraglutide acts directly and indirectly in LDL and VLDL catabolism, increases lipoprotein lipase gene expression responsible for TAG hydrolysis, and reduces apolipoprotein B48, diacylglycerol O -acyltransferase 1, and microsomal transfer protein gene expression, all of which are involved in chylomicron synthesis [77, 78]

As compared to mono or coagonists, the triagonist had enhanced effectiveness to decrease body weight and fat mass in rodents

JAMA Cardiol 2020

The incidence of acute pancreatitis with GLP-1 receptor agonist therapy in individuals with a known history of pancreatitis

If youre actively trying to lose weight through lifestyle changes and add the use of one of these medications, research has shown that the drugs may lead to around 6 to 9 pounds (2.8 to 4.2 kg) of additional weight loss