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These theories all come into play in some of the preclinical studies of GLP-1 RAs in animals, where it was demonstrated that GLP-1 RAs can reduce dopaminergic neuron loss and improve motor function

"So, the recommendation currently is to stop the medication prior to conception," Maya said

Furthermore, the weight loss induced by tirzepatide appears to be primarily due to a greater reduction in fat mass compared to metabolically active lean mass, resulting in a favorable redistribution of abdominal ectopic adipose tissue and a marked reduction in waist circumference and intrahepatic fat [54]

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Future Warnings Alison Cave, Chief Safety Officer of the MHRA, said: For the vast majority of patients who are prescribed GLP-1s, they are safe and effective medicines which deliver significant health benefits

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