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Leptin levels decline as the fat percentage decreases, resulting in less leptin resistance

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So far, several unimolecular dual and triple agonists are in clinical evaluation and as of today, the improved metabolic efficacy does not seem to be compromised by reduced safety [25].

Approximately 110 6 cells per sample were incubated with serial dilutions of the antibody in staining buffer for 60 minutes at 4C

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Determination of p-Smad3 and p-AMPK expression The protein expression levels of the p-Smad3 and phosphorylated AMP-activated protein kinase (p-AMPK) were analyzed using the western blot technique