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Individual safety outcomes, whether serious bacterial infections or urinary tract and digestive side effects, were generally lower risk compared to the comparison groups

The term nonresponder refers to people who do not experience a meaningful benefit after an adequate dose and duration, and "meaningful" has a specific clinical definition: losing at least 5% of starting body weight, a threshold associated with health improvements

Only the numbers you plug in differ

Nearly half of everyone on high-dose semaglutide experienced nausea at some point during the trial