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They should also receive periodic evaluations from a physician experienced in managing obesity, GLP-1RAs, and the principles of CBT for BED

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Although I would recommend TRT to almost everyone over 50, this condition can affect people much younger, probably caused by excessive stress

The human evidence is real, it is early, and it is specific: GLP-1 went up, and metabolic benefits showed up mostly in the people who had the most room to improve

It is essential to view these dietary and lifestyle changes not as a temporary "diet" undertaken solely while on medication, but as the foundation for long-term health and well-being

doi:10.1053/j.gastro.2020.12.031