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Description
To accommodate GLP-2 rather than GLP-1, GLP-2R fine-tunes the conformations of the extracellular parts of transmembrane helices (TMs) 1, 5, 7 and extracellular loop 1 (ECL1)

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Larger randomized controlled trials with long-term follow-up are necessary to confirm these associations and evaluate the risk-benefit ratios
SGLT2GLP-1

Some data suggests that a meaningful portion of weight lost on GLP-1 medications can come from lean mass
