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Gastric sleeve surgery reduces stomach volume and speeds gastric emptying, both of which compromise oral medication absorption

As millions adopt medications like semaglutide and tirzepatide, aesthetic concerns linked to rapid fat loss (commonly called "GLP-1 face") are becoming more visible

This type of cancer occurs when there's a growth of abnormal cells in the lower part of the colon that connects the anus to the large bowel

But their use remains controversial, particularly for primary prevention (people without established heart disease)

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Three obese, non-diabetic patients received GLP-1 receptor agonists off-labelthat is, agents not (yet) formally approved for the treatment of obesity
