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Description
Cardiovascular outcome trials (CVOTs) in people living with type 2 diabetes mellitus and obesity have confirmed the cardiovascular benefits of glucagon-like peptide 1 receptor agonists (GLP-1RAs), including reduced cardiovascular mortality, lower ...

Introduction Significant reductions in cardiovascular events, all-cause mortality, and the advancement of kidney disease are demonstrated by important studies such as FLOW
Learn what they contain, what the science actually says, and what truly supports people using GLP-1 medications.

We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity

Unlike FDA-approved medications (e.g., Wegovy, Ozempic, Zepbound), compounded alternatives lack agency review for safety, quality, and efficacy

Additionally, we highlight the gaps for further studies in clinical applications of GLP-1 RAs in aging-related diseases
