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Teaching old receptors new tricks: biasing seven-transmembrane receptors

Recent findings on GLP-1 have raised concerns regarding their impact on fetal development, especially considering limited human studies and substantial reliance on animal models

U., Detraux, J., De Lepeleire, J

Further large-scale, high-quality randomized controlled trials are essential to definitively establish the long-term efficacy and safety of this approach

Besides, previous studies in mice models of AD showed that linagliptin could decrease A accumulation, attenuate tau phosphorylation and inhibit neuroinflammation (83)

Vilsbll T, Bain SC, Leiter LA, et al