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Cardiovascular Outcomes Liraglutide (LEADER trial): 13% reduction in major adverse cardiovascular events (MACE) in patients with Type 2 diabetes and high cardiovascular risk Statistically significant cardiovascular protection Semaglutide (SELECT trial): 20% reduction in MACE in patients with obesity and established cardiovascular disease Studied specifically for cardiovascular outcomes in obesity (not just diabetes) Both medications provide cardiovascular protection, but semaglutides evidence is more recent, more robust, and specifically applicable to patients with obesity regardless of diabetes status

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420,421 Patients are advised to reduce excessive intake of acidic foods to prevent exacerbation of UC symptoms

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Youll receive monthly meetings and treatment plans from your nurse care practitioner and instructions for how to inject the medication safely at home

PloS one, 8(6), e67482