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These areas are not currently FDA-cleared indications

Imagine switching to different GLP-1 agonists that havent been wiped out, or buddying up with new therapeutic routes
Bariatric surgical methods provide more effective and long-lasting outcomes and carry a relatively higher risk of complications, which limits their widespread adoption
It is associated with a wide range of physical comorbidities, including type 2 diabetes, cardiovascular disease, hypertension, and musculoskeletal disorders [1,2,3]

Milton Packer discussing the history of ARNI