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These results may herald the beginning of pharmaceutical management of excess weight with potential to reduce morbidity and mortality, analogous to treatment of hyperglycemia, dyslipidemia and hypertension

An increasing concentration of unlabeled GLP-2(133) or teduglutide (ranging from 0.1 nM to 1 M) followed by a fixed concentration of [ 125 I]GLP-2(133, M10Y) (1015 pM) was added to the cells and incubated for 4 h at 4 C

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People who maintain extreme restrictions indefinitely develop an unhealthy relationship with food, miss out on nutrition from eliminated food groups, and set themselves up for binge eating when the restrictions inevitably break down

Personalized treatment approaches matter

Due to its significant weight loss effects, tirzepatide has also shown potential in managing conditions like non-alcoholic fatty liver disease (NAFLD), though further research is necessary (43)(46)