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We believe MEDI4166 is a novel molecule combining long acting agonist peptide and neutralising antibody activities to deliver a unique pharmacology profile for the management of T2D.

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Glucagon-like peptide-1 receptor agonists also lead to satiety and appetite reduction through action on the brains appetite regulation centers, leading to weight loss in obese patients

Specifically, GLP-1 RAs showed significantly reduced risks of progression to systolic heart failure (HR 0.60) and stroke (HR 0.75) compared to SGLT2 inhibitors

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