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This data was vital for regulatory approval and understanding the broader physiological effects of GLP-1 receptor agonist drugs

Currently, the first randomized, double-blind phase III trial is underway to evaluate the effects of oral Semaglutide in AD prevention and progression

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The conventional functions of GLP-1 are associated with its capacity to boost insulin secretion in response to glucose stimulation

A pre-clinical study showed that exendin-4 had a remarkable neuroprotective effect, improving the neurological deficit caused by transient middle cerebral artery occlusion in mice, and reducing neuronal loss and microglial inflammation (82)