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2 GLP-1R monotherapy (e.g., semaglutide) is highly effective, but dual GLP-1R/GIPR agonists (e.g.,

In conclusion, GLP-1 RAs are an intriguing multitarget treatment option for people with NDs, and future research should focus on optimizing treatment for clinical trials, evolved agonists that can penetrate the central nervous system (CNS), and combination therapies.

When combined with a balanced diet and exercise, it may support healthy weight management and overall wellbeing

Widespread access to GLP-1 therapies could generate significant benefits to society and produce huge savings for Medicare, Schaeffer research shows

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